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Weeks Tirzepatide dose Notes 14 2.5 mg Initiation only (not for glucose/weight effect) 58 5 mg First maintenance option 912 7.5 mg Increase as tolerated 1316 10 mg Maintenance option 1720 12.5 mg Increase as tolerated 21+ 15 mg (max) Maximum maintenance dose These steps follow the Mounjaro FDA label and Zepbound FDA label
W.J.H., Elders, P.J.M., Lips, P., Dhonukshe-Rutten, R.A.M., Van Schoor, N.M., and De Groot, L.C.P.G.M
Presented for research literature review only Borvinskaya EV et al
The resulting decrease in functional calcitriol, as a result of FGF23 action, limits the intestinal absorption of calcium and phosphate
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